Most pupular items http://www.cangenetest.org/ 2008-11-20T19:54:38-05:00 text/html 2008-10-16T18:36:48-05:00 http://www.cangenetest.org/ Giovanni Parmigiani and al. http://www.cangenetest.org/url.php?i=1122&f=News The objective of this study was to systematically quantify the accuracy of the following publicly available models to predict mutation carrier status: BRCAPRO, family history assessment tool, Finnish, Myriad, National Cancer Institute, University of Pennsylvania, and Yale University. The authors observed that the 7 models differed in their predictions. The better-performing models have a c-statistic around 80%. BRCAPRO has the largest c-statistic overall and in all but 2 patient subgroups, although the margin over other models is narrow in many strata. Outside of high-risk populations, all models have high false-negative and false-positive rates across a range of probability thresholds used to refer for mutation testing. text/html 2008-10-16T18:27:23-05:00 http://www.cangenetest.org/ http://www.cangenetest.org/url.php?i=1117&f=News Researchers from Stanford University, California have developed a new test which carries no increased risk of miscarriage because it uses samples of the mother's blood, rather than samples of amniotic fluid, to detect whether the extra chromosome which causes Down's syndrome is present. Original document: <a href=" http://www.pnas.org/content/early/2008/10/03/0808319105.abstract?sid=7f3211cc-cff7-4f67-9453-11af6c856e25"> Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood </a> text/html 2008-10-16T18:45:23-05:00 http://www.cangenetest.org/ Bridget M. Kuehn http://www.cangenetest.org/url.php?i=1126&f=News New technologies that allow scientists to rapidly analyze a person's genome for potentially deleterious variations are now being used by at least 1 company and an academic medical center for prenatal testing, igniting a debate among scientists about the clinical value and ethical implications of the procedure. This debate is explored here. text/html 2008-10-16T18:53:10-05:00 http://www.cangenetest.org/ http://www.cangenetest.org/url.php?i=1133&f=News The aim of the Society for Genomics, Policy and Population Health is to provide a forum for those with an interest in the impact of genetic and molecular science on population health, attracting to its membership lawyers, philosophers, social scientists, public health professionals and policy makers as well as geneticists and molecular scientists. The Society will focus on the policy and the ethical, legal and social issues raised by genomic and post-genomic science and technologies.